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Students explore the concept of homeostasis using arterial blood pressure as an example. The interaction of variables related to heart rate, vessel radius, blood viscocity, and stroke volume can be studied by direct manipulation, or indirectly through interventions, such as hemorrhage, exercise, dehydration, shock, intravenous infusion, epinephrine, and foxglove. Nerve impulses can be monitored under the experimental conditions. Realistic case studies such as hypertension and congestive heart failure are also available for investigation.